Drug Panel

The drug panel is a tab-delimited file that stores information about the drugs that Drabme will test on it’s input models. In each line, a drug name is given along with the name of its targets and the effect that drug has on them. The effect must be either the inhibits or activates keyword and the targets must be in the initial network otherwise there is an error.

An example of a drug panel file is the following:

A   inhibits   A1
B   inhibits   B1   B2
C   activates   C1

A, B and C are the drug names and A1, B1, B2 and C1 the respective targets.

If the user does not specify a perturbations file in Drabme’s input files (which is not required), the drugs that are listed in the drug panel (above example: A, B and C) are used to generate all possible combinations of perturbations up to the size number specified in the respective configuration.